Can Humira Really Cause Weight Loss? | Prime MD Plus. See our doctor in the DFW area

Can Humira Really Cause Weight Loss?

Dr. Divya Javvaji, MD
Prime MD Plus

Humira, a medication prescribed to treat rheumatoid arthritis and other autoimmune diseases, has become one of the most widely used prescription medications in the world.

But is there any evidence that Humira can cause weight loss?

Can Humira Really Cause Weight Loss?

This question has been the subject of much discussion in the medical community, with some studies suggesting that Humira can lead to weight loss in some patients.

However, the research into this possible side effect of Humira is still inconclusive. While some studies have found evidence of weight loss, others have not.

This leaves many patients and doctors wondering if Humira could be a possible solution for weight loss.

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Surprising Benefits of Humira: How this Treatment Can Improve Your Health

Humira, a drug used to treat a variety of autoimmune diseases, has become increasingly popular in recent years.

This medication is used to treat conditions such as Crohn’s disease, ulcerative colitis, rheumatoid arthritis, psoriatic arthritis and other diseases.

Humira works by inhibiting an inflammatory response in the body.

It works by blocking a specific protein, called tumor necrosis factor alpha, from attaching to its receptor on cells.

This prevents the body from producing the proteins and cytokines that cause inflammation, and this process helps reduce the symptoms of autoimmune diseases.

Humira is administered by subcutaneous injection, typically once every two weeks.

It typically takes about two weeks for Humira to begin to work, and the effects can last up to a month.

The most common side effects of Humira include injection site reactions, upper respiratory infections, and headaches.

In rare cases, Humira can cause serious infections, including tuberculosis and other infections.

It is important to speak to your doctor before starting Humira to ensure that it is the right treatment for your condition.

Humira has been demonstrated to be an effective and safe treatment for a variety of autoimmune diseases.

Studies have shown that Humira can reduce inflammation and improve symptoms in patients with Crohn’s disease and ulcerative colitis.

It is also an effective treatment for rheumatoid arthritis, psoriatic arthritis, and other autoimmune diseases. 

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Shocking Results: See How Humira Impacts Your Weight

Humira (adalimumab) is a biologic drug used to treat a wide range of autoimmune diseases.

It is a monoclonal antibody, meaning it is designed to target specific cells in the body.

One of the side effects of Humira is a change in weight.

Humira works by blocking a protein called tumor necrosis factor (TNF).

TNF is a cytokine produced by the body that can cause inflammation and tissue damage in people with autoimmune diseases.

By blocking TNF, Humira can reduce the severity of these symptoms.

However, when TNF is blocked, it can also lead to weight changes. In some cases, Humira can cause weight gain.

This is due to the fact that TNF is involved in the regulation of energy balance.

Blocking TNF can affect the body’s ability to maintain a healthy weight.

In other cases, Humira can cause weight loss. This is due to the fact that Humira can cause nausea and appetite suppression.

These side effects can lead to decreased food intake, which can result in weight loss.

It is important to note that these weight changes are usually not severe, and they usually resolve once the body adjusts to the drug.

If you are taking Humira and notice a sudden change in your weight, it is important to speak to your physician.

They can help you manage your weight and ensure that you are taking the right dosage.

Unbelievable: Does Humira Really Cause Weight Loss?

In conclusion, Humira appears to not be a direct cause of weight loss.

While there have been anecdotal reports of patients experiencing weight loss upon taking Humira, there is no scientific evidence to support this.

For those concerned about the potential for weight loss from Humira, the best option is to speak with a healthcare provider about their individual concerns and the potential risks and benefits of taking the medication.

Humira is a powerful medication and should be taken only under the supervision of a healthcare professional.

While it may be tempting to take advantage of potential side effects, such as weight loss, it is important to remember that the medication is designed to treat specific medical conditions and should not be taken lightly.

By consulting with a healthcare provider, one can make an informed decision about whether or not Humira is the right choice for their individual needs.

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Miracle Drug or Harmful Side Effects? Find Out What Humira Does to Your Body

Humira (adalimumab) is a biologic therapy used to treat a variety of inflammatory diseases, including rheumatoid arthritis, Crohn’s disease, ulcerative colitis, psoriasis, and ankylosing spondylitis.

It works by blocking a molecule called tumor necrosis factor-alpha (TNF-alpha), which plays a role in inflammation.

Physiologically, Humira has several effects on the body:

  • Reduction in inflammation: Humira works by blocking TNF-alpha, which is involved in inflammation. By blocking this molecule, Humira helps reduce inflammation and its associated symptoms, such as joint pain, swelling, and stiffness.
  • Improved immune system function: Humira helps to reduce inflammation, which can help the immune system function more effectively. This can help to reduce the risk of infection and other immune-related diseases.
  • Improved quality of life: By reducing inflammation and improving immune system function, Humira can improve the quality of life for people with chronic inflammatory diseases.
  • Improved joint health: Humira can help reduce inflammation and improve joint health. This can help to reduce joint pain and stiffness, improve mobility, and reduce the risk of joint damage.
  • Reduced risk of cancer: Some studies have suggested that Humira may reduce the risk of certain types of cancer, including non-Hodgkin’s lymphoma and skin cancer.

The Impact of Humira on Weight Loss and Infection Risk in Chronic Diseases

While weight loss is not a common side effect of Humira, there are some ways in which the medication can indirectly contribute to weight loss.

One way is through the increased risk of infections that can occur with the use of Humira.

Humira works by suppressing the immune system, which can make patients more susceptible to infections.

Infections can cause symptoms such as fever, fatigue, shortness of breath, and decreased appetite, all of which can contribute to weight loss.

In addition, certain infections, such as fungal infections, can affect the gastrointestinal system and lead to digestive issues that may result in weight loss.

Furthermore, chronic diseases such as inflammatory bowel disease or rheumatoid arthritis, which are treated with Humira, can also cause weight loss due to symptoms such as loss of appetite, muscle aches, and fatigue.

The impact of Humira on weight loss and infection risk in chronic diseases is a complex issue that requires careful consideration.

While weight loss is not a common side effect of Humira, it can indirectly contribute to weight loss through increased risk of infections.

Humira works by suppressing the immune system, making patients more susceptible to infections.

Infections can cause symptoms such as fever, fatigue, stomach pain, chest pain and decreased appetite , all of which can contribute to weight loss.

Additionally, chronic diseases that are treated with Humira can also cause weight loss due to symptoms such as loss of appetite and fatigue.

Therefore, it is important for patients taking Humira to be aware of the potential risks and to work closely with their health care provider to monitor their weight and overall health.

By staying informed and proactive, patients can ensure that they are receiving the best possible care and support while taking Humira.

Exploring the Potential for Weight Loss with Humira: Understanding Drug Interactions and Allergic Reactions

When considering the potential for weight loss with Humira, it is important to also take into account possible drug interactions and allergic reactions that may impact a patient’s weight.

Drug combinations can occur when different medications are taken together, leading to changes in how each medication works in the body.

Some medications may interact with Humira in a way that could potentially lead to weight loss as a side effect.

For example, certain medications used to treat conditions such as diabetes, high blood pressure, liver disease or depression may have adverse effects that include weight loss.

If these medications are taken in combination with Humira, the potential for weight loss may be increased.

Additionally, allergic reactions to Humira can also impact a patient ‘s weight. An allergic reaction to Humira can cause symptoms such as hives, itching, swelling, poor appetite and difficulty breathing.

In severe cases, an allergic reaction can lead to anaphylaxis, a life-threatening emergency that requires immediate medical attention.

In some cases, severe allergic reactions to medications can impact a patient’s weight due to the stress on the body and potential for fluid retention or other metabolic changes.

Humira products use a needle cover containing natural rubber latex, unsuitable for those with a rubber allergy. 

While weight loss is not a common side effect of Humira, it is important for patients to be aware of the potential risks and to discuss any concerns with their health care professional.

Frequently Asked Question

Here are some common questions on Humira causing weight loss.

Can chronic diseases treated with Humira lead to weight loss?

Chronic diseases treated with Humira, such as rheumatoid arthritis, psoriatic arthritis, Crohn’s disease, psoriasis, and others, can sometimes lead to weight loss.

However, it’s important to understand that the weight loss associated with these conditions is often due to factors beyond the direct effect of Humira.

Many chronic diseases treated with Humira, like rheumatoid arthritis, idiopathic arthritis, hidradenitis suppurativa and Crohn’s disease, can cause symptoms that contribute to weight loss.

These symptoms may include loss of appetite, digestive issues, fatigue, shortness of breath and muscle weakness.

When the body is dealing with the inflammation and discomfort associated with these conditions, it can lead to a decrease in appetite and overall food intake, resulting in weight loss.

The severity of the chronic disease also plays a role.

In conditions like severe rheumatoid arthritis, where joint pain and stiffness can limit mobility and physical activity, individuals may burn fewer calories, which can contribute to weight loss over time.

Humira works by suppressing the immune system to reduce inflammation in the body.

While this can be beneficial for treating autoimmune diseases, it also comes with the risk of increased susceptibility to infections. Infections, especially chronic ones, can cause symptoms like fever, fatigue, chronic (long-term) pain, painful skin sores and decreased appetite, leading to weight loss.

Inflammatory bowel diseases like Crohn’s disease and ulcerative colitis, which are treated with Humira, can lead to digestive issues such as diarrhea, abdominal pain, and malabsorption of nutrients.

These digestive issues can result in loss of body fat due to the body’s inability to properly absorb and utilize nutrients from food.

It’s important to remember that individual factors also play a significant role in weight loss.

Factors like age, overall health, dietary habits, physical activity levels, and genetic predispositions can all influence weight changes in individuals with chronic diseases treated with Humira.

How do healthcare providers determine if weight loss in a patient is related to Humira?

When assessing whether weight loss in a patient is related to Humira, healthcare providers typically follow a systematic approach that involves evaluating various factors and conducting thorough examinations. 

Healthcare providers start by reviewing the patient’s health history, including any previous or current medical conditions, medications, treatments, and surgeries.

They pay particular attention to autoimmune diseases for which Humira is prescribed, such as rheumatoid arthritis, psoriasis, Crohn’s disease, and ulcerative colitis. 

For instance, history of liver damage, lung infection, sinus infection or Hepatitis B infection might affect weight management.

A comprehensive physical examination is conducted to assess the patient’s overall health, including vital signs, body composition, and signs of inflammation or infection.

Any changes in weight caused by antirheumatic drugs, such as sudden weight gain or loss, are noted and investigated further.

Healthcare providers inquire about specific symptoms associated with the patient’s condition and treatment with Humira.

Symptoms such as nausea, appetite changes, gastrointestinal issues, and risk for infection in adults are carefully evaluated.

Blood tests are often performed to assess various parameters, including liver function, white blood cell count, inflammatory markers, and signs of infection.

Abnormalities in these lab tests may indicate underlying issues that could contribute to weight loss.

In some cases, imaging studies such as X-rays, ultrasounds, or MRIs may be ordered to evaluate the patient’s internal organs and detect any abnormalities that could be contributing to weight loss.

Healthcare providers review all medications the patient is currently taking, including Humira and any other prescription or over-the-counter drugs.

They assess potential active drug interactions or side effects for active infections that could lead to weight loss.

Depending on the patient’s symptoms and medical history, licensed healthcare professionals may consult with specialists such as gastroenterologists, rheumatologists, or infectious disease specialists to gain additional insights into the possible causes of weight loss.

Healthcare providers may monitor the patient’s weight, symptoms and health conditions over time to determine if there is a consistent pattern or trend associated with the use of Humira.

What is the required treatment plan for dietary and lifestyle recommendations in patients on Humira to manage weight?

Managing weight while on Humira requires a holistic approach tailored to individual needs.

For patients with autoimmune diseases like rheumatoid arthritis or psoriasis, weight management is crucial amidst potential complications such as liver failure or lymphoma.

Lifestyle adjustments are key, including a balanced diet rich in nutrients to support overall health and minimize side effects like plaque psoriasis or scaly patches.

Patients should stay hydrated, control portions, and monitor sugar intake to mitigate risks such as heart failure or swollen glands.

Exercise, stress management, and adequate sleep play vital roles in maintaining weight stability and reducing risks associated with Humira, like infections or chronic inflammatory conditions.

Healthcare providers monitor patients closely for signs of weight loss or adverse reactions, considering factors like disease activity, nervous system reactions, or the presence of rheumatic diseases.

Collaborating with specialists helps tailor treatment plans to individual needs, ensuring patients receive comprehensive care while managing conditions like inflammatory bowel disease or severe hidradenitis suppurativa.

What are the potential risks and side effects of taking Humira for weight loss without a prescription?

Taking Humira for weight loss without a prescription poses significant risks and potential side effects that individuals should be aware of.

Humira, also known as adalimumab, is a potent medication primarily used to treat autoimmune diseases in patients with rheumatoid arthritis, Crohn’s disease, ulcerative colitis, psoriasis, and ankylosing spondylitis.

While some studies have suggested a correlation between Humira use and weight loss, it’s essential to understand the potential dangers associated with off-label usage for weight management.

One of the critical risks is the suppression of the immune system.

Humira works by inhibiting the activity of tumor necrosis factor alpha (TNF-alpha), a protein involved in the inflammatory response.

By dampening the immune system, Humira increases susceptibility to infections.

Individuals taking Humira without proper medical supervision may experience more frequent and severe infections, including respiratory infections, urinary tract infections, and skin infections.

Moreover, infections can lead to symptoms such as fever, fatigue, blood in phlegm and decreased appetite, which can contribute to weight loss.

Furthermore, Humira use without medical guidance can exacerbate existing medical conditions or lead to the development of new ones.

For example, individuals with a history of autoimmune diseases like lupus-like syndrome, chronic plaque psoriasis, Guillain-Barre syndrome or rheumatoid arthritis may experience flare-ups or worsening of symptoms.

Additionally, Humira has been associated with an increased risk of certain types of cancer, including cell lymphoma, types of skin cancer and a type of cancer called hepatosplenic T-cell lymphoma.

Also, in congestive heart failure, nervous system disease, inflammatory reactions and other long-term side effects. 

Using Humira for weight loss without proper monitoring may heighten these risks, leading to serious health complications.

Another potential side effect of off-label Humira use is adverse reactions at the injection site.

Mild side effects include redness, swelling, itching, or pain at the injection site.

In some cases, individuals may develop more severe reactions such as skin infections or abscess formation.

Without medical supervision, individuals may overlook these side effects or misinterpret them, leading to delayed treatment and potentially worsening conditions.

Moreover, Humira can have systemic effects on various organs and systems in the body. Individuals may experience gastrointestinal symptoms like nausea, vomiting, diarrhea, or abdominal pain.

Liver dysfunction, indicated by dark urine or yellowing of the skin and eyes (jaundice), can also occur.

These symptoms may be indicative of serious underlying issues such as liver failure, which requires immediate medical attention and major surgery.

Additionally, long-term use of Humira without medical oversight may lead to the development of drug resistance or decreased effectiveness over time.

This phenomenon, known as treatment failure, can result in the progression of underlying diseases and the need for alternative treatment options.

Moreover, abrupt discontinuation of Humira can lead to withdrawal symptoms, including worsening of symptoms, rebound inflammation, or disease flares.

Does Humira cause weight loss in pregnant and nursing women?

The effects of Humira (adalimumab) on weight loss in pregnant and nursing women are a topic of concern and should be thoroughly discussed with healthcare providers.

While Humira is primarily used to treat autoimmune diseases like rheumatoid arthritis, Crohn’s disease, ulcerative colitis, psoriasis, and ankylosing spondylitis, its potential impact on weight loss during pregnancy and breastfeeding requires careful consideration.

Clinical trials and studies specifically evaluating the effects of Humira on pregnant and nursing women are limited.

The package insert for Humira includes a warning about the potential risk to pregnant women and advises against using the medication during pregnancy like birth defects unless the potential benefits outweigh the risks.

During pregnancy, the decision to continue or discontinue Humira treatment should be made in consultation with a healthcare provider, taking into account the specific medical condition being treated and the potential risks to both the mother and the fetus.

Humira is classified as a Pregnancy Category B medication, indicating that animal reproduction studies have not demonstrated a risk to the fetus, but there are no adequate and well-controlled studies in pregnant women.

Sexually active persons should ask their doctor for birth control while taking Humira.

For nursing women, Humira may be present in breast milk, although the amount is likely to be minimal.

There is limited information available regarding the effects of Humira on a breastfed child.

Therefore, nursing women should weigh the potential benefits of breastfeeding against the potential risks of Humira exposure to the infant.

Healthcare providers can provide medical advice on breastfeeding while taking Humira, considering individual circumstances and the infant’s health.

Final Take

In conclusion, while there is evidence suggesting that Humira may indirectly contribute to weight loss through various mechanisms, such as increased susceptibility to infections and the symptoms associated with chronic diseases like rheumatoid arthritis and inflammatory bowel disease, its direct role in causing weight loss remains inconclusive.

The impact of Humira on weight loss is complex and multifaceted, influenced by factors such as individual patient characteristics, disease activity, and treatment duration.

Furthermore, the decision to use Humira, whether for its intended therapeutic purposes or off-label for weight loss, should be made in consultation with a healthcare provider, taking into account the potential risks and benefits.

Additionally, as research on Humira continues to evolve, it is important for healthcare providers to remain vigilant in monitoring patients for any signs of weight loss or adverse effects associated with its use.

Regular assessment of the level of disease activity, nutritional status, immune reactions and overall health is essential in ensuring that patients receive appropriate care and support while on Humira therapy.

Ultimately, the goal is to optimize patient outcomes and improve quality of life while minimizing potential risks and adverse effects associated with the use of this medication.

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