Menopause, High Cholesterol, and Longevity: Examining the Link

Menopause, High Cholesterol, and Longevity: Examining the Link

Dr. Divya Javvaji, MD
Prime MD Plus

As a medical expert, I am often asked about the various factors that can impact a woman’s health as she ages. One topic that frequently comes up is the relationship between menopause, high cholesterol, and longevity. It’s a fascinating area of study that sheds light on the complex interplay between hormones, cardiovascular health, and overall well-being.

In this article, we will delve into the connection between menopause and high cholesterol, exploring whether menopause causes high cholesterol and the reasoning behind it. We will also discuss how menopause can impact one’s health and longevity, providing valuable insights for women navigating this transformative phase of life.

Discover Your Path to a Longer, Healthier Life!

Take our free quiz to see how your lifestyle measures up to the world's longest-living communities and receive expert tips for a healthier, longer life.

Take the Quiz

Does Menopause Cause High Cholesterol?

Many women experience an increase in cholesterol levels during and after menopause. This can be attributed to several factors, including hormonal changes and shifts in metabolism. Estrogen, a hormone that plays a crucial role in maintaining healthy cholesterol levels, declines significantly during menopause. Estrogen helps to increase the levels of high-density lipoprotein (HDL) cholesterol, often referred to as “good” cholesterol, which helps to remove low-density lipoprotein (LDL) cholesterol, or “bad” cholesterol, from the bloodstream.

Additionally, menopause is associated with changes in fat distribution and an increase in abdominal fat. This type of fat, known as visceral fat, is particularly metabolically active and can lead to an imbalance in cholesterol levels. As a result, LDL cholesterol may rise, while HDL cholesterol may decrease, leading to an unfavorable lipid profile.

How Menopause Can Affect Your Health and Longevity?

Understanding the impact of menopause on cholesterol levels is vital, as high cholesterol is a known risk factor for cardiovascular disease, a leading cause of morbidity and mortality among women. The combination of menopause and high cholesterol can increase the risk of developing heart disease, stroke, and other cardiovascular conditions.

  1. Increased risk of atherosclerosis: High cholesterol levels contribute to the formation of plaque in the arteries, a condition known as atherosclerosis. Menopause can exacerbate this process, potentially leading to narrowed or blocked arteries, which can increase the risk of heart attack or stroke.
  2. Reduced vascular elasticity: Estrogen has a protective effect on blood vessels, helping to maintain their elasticity and flexibility. As estrogen levels decline during menopause, blood vessels may become less elastic, further increasing the risk of cardiovascular complications.
  3. Metabolic changes: Menopause is often associated with weight gain and changes in metabolism. High cholesterol, coupled with these metabolic changes, can contribute to insulin resistance, type 2 diabetes, and an increased risk of metabolic syndrome.

It is important to note that while menopause may bring about changes in cholesterol levels, it is not the sole determinant of cardiovascular health and longevity. Lifestyle factors, such as diet, physical activity, and smoking, also play a significant role. By adopting a healthy lifestyle and working closely with healthcare professionals, women can effectively manage cholesterol levels and mitigate the potential impact of menopause on their overall health and longevity.

Compare Longevity by U.S. States

Lifespan Comparison Tool

Compare the life expectancy by the U.S. State

In the Dallas-Fort Worth Metroplex?

Discover how our cutting-edge medical practice enhances longevity. Detect dementia years in advance, assess your vascular age, and proactively monitor crucial indicators to prevent major issues.

Learn More

Data Source

The data presented on lifespan trends comes from, a highly reputable platform that provides comprehensive demographic data on mortality rates worldwide. It’s a collaborative project of respected research institutions such as the Department of Demography at the University of California, Berkeley; the Max Planck Institute for Demographic Research; and INED – French Institute for Demographic Studies.’s datasets are trusted globally by researchers and policy makers due to their rigorous research methods and commitment to privacy and ethical guidelines. As such, readers can be confident that our report offers precise insights into the lifespan trends backed by authoritative research.

Want to Consult With Our Doctor?


Call Now:

452 TX 121, Suite 130, Coppell, TX 75019


Verified by

Copyright © 2024 Prime MD Plus. All rights reserved